Nek2 kinase is a serine/threonine-protein kinase that plays a crucial role in the regulation of the cell cycle, particularly during mitosis. It belongs to the NIMA-related kinase (Nek) family, which is essential for proper cell division and genomic stability. Nek2 is predominantly localized in the centrosome, a key cellular structure responsible for organizing microtubules and ensuring accurate chromosome segregation.