How to Interpret Cytochrome c Oxidase Staining Results?
Interpreting COX staining results involves comparing the staining intensity and pattern in different tissues or cells. Healthy tissues with normal mitochondrial function will show uniform and strong staining, indicating high COX activity. In contrast, tissues with mitochondrial dysfunction will exhibit reduced or absent staining, suggesting impaired COX activity. Additionally, patchy or uneven staining may indicate heteroplasmic mitochondrial DNA mutations.
