What are the Applications of Cytochrome c Oxidase Staining?
Cytochrome c oxidase staining has several important applications, including:
Mitochondrial Disease Diagnosis: Detecting deficiencies in COX activity can help diagnose conditions such as mitochondrial myopathies and Leigh syndrome. Cancer Research: Assessing mitochondrial function in cancer cells can provide insights into the metabolic adaptations that support tumor growth and survival. Neuroscience: Studying COX activity in neuronal tissues can shed light on neurodegenerative diseases and brain metabolism. Muscle Pathology: Evaluating COX activity in muscle biopsies can help diagnose muscular dystrophies and other myopathies.