What Techniques are Used to Study LTD in Histology?
Several techniques are employed to study LTD at the histological level. Electrophysiological recordings, such as patch-clamp and field recordings, are used to measure synaptic responses before and after induction of LTD. Immunohistochemistry and confocal microscopy can visualize changes in receptor distribution and synaptic proteins. Additionally, techniques like Western blotting and mass spectrometry can quantify protein phosphorylation and other post-translational modifications associated with LTD.
