What is the Structural Composition of SERCA Pumps?
SERCA pumps are complex proteins composed of multiple domains. The transmembrane domain forms the pathway for Ca²⁺ ions, while the nucleotide-binding domain (N) binds ATP. The actuator domain (A) is involved in the conformational changes necessary for ion transport, and the phosphorylation domain (P) is where ATP is hydrolyzed.