In [histological studies](), SERCA pumps can be examined using various techniques such as immunohistochemistry, Western blotting, and electron microscopy. Immunohistochemistry allows for the localization of SERCA proteins within tissue sections, while Western blotting provides information on protein expression levels. Electron microscopy offers detailed visualization of the ultrastructure of the sarcoplasmic and endoplasmic reticulum where SERCA pumps reside.
