SERCA (Sarco/Endoplasmic Reticulum Ca²⁺-ATPase) pumps are a class of membrane-bound enzymes responsible for the active transport of calcium ions (Ca²⁺) from the cytosol into the sarcoplasmic and endoplasmic reticulum. These pumps play a critical role in maintaining intracellular calcium homeostasis, which is vital for various cellular processes, including muscle contraction, signal transduction, and cell proliferation.
