What is the Role of the Extracellular Matrix in the Osteoblastic Niche?
The extracellular matrix (ECM) provides a scaffold for cellular attachment and a reservoir for growth factors and cytokines. Components of the ECM, such as collagen, fibronectin, and laminin, create a supportive environment that influences cell behavior through biochemical and mechanical signals. The ECM is dynamic and can be remodeled by osteoblasts and other cells within the niche to adapt to physiological needs.
