How is the Osteoblastic Niche Involved in Hematopoiesis?
The osteoblastic niche plays a vital role in hematopoiesis by providing a supportive environment for HSCs. The niche regulates HSC quiescence, self-renewal, and differentiation through various signaling pathways. Disruption of the niche can lead to hematopoietic disorders, such as anemia or leukemia, highlighting the importance of this microenvironment in blood cell production.
