Reed-Sternberg cells are distinctive, large, abnormal cells typically found in patients diagnosed with Hodgkin lymphoma. These cells are crucial for the histological diagnosis of this type of lymphoma. Named after the pathologists Dorothy Reed and Carl Sternberg, who first described them, Reed-Sternberg cells are generally multinucleated or have a bilobed nucleus with prominent nucleoli, giving them an "owl's eye" appearance.
