What is the Role of O-Glycosidic Linkages in Glycoproteins?
In glycoproteins, O-glycosidic linkages are integral to their structure and function. They influence protein folding, stability, and interactions with other molecules. These linkages also play a role in cell-cell recognition, signaling, and immune responses. For example, the O-linked glycosylation in mucin proteins enhances their protective function in epithelial tissues by providing a hydrated gel-like layer.
