What is the Importance of O-Glycosidic Linkages in Disease?
Aberrations in O-glycosidic linkages can lead to various diseases. For instance, altered glycosylation patterns are observed in cancer cells, affecting tumor growth and metastasis. In addition, defects in glycosylation enzymes can cause congenital disorders of glycosylation, impacting multiple organ systems. Understanding these linkages can aid in the development of diagnostic and therapeutic strategies for such diseases.
