What is the Role of IL-4 in Inflammation and Allergies?
IL-4 plays a pivotal role in the development and maintenance of allergic inflammation. It promotes the class switching of B cells to produce IgE antibodies, which are central to allergic reactions. IL-4 also enhances the survival and recruitment of eosinophils and mast cells to the site of inflammation, contributing to the histological features observed in allergic tissues.
