What Is the Clinical Relevance of Non-Coding RNAs?
Non-coding RNAs have significant clinical relevance as biomarkers and therapeutic targets. Aberrant expression of ncRNAs is associated with various diseases, including cancer, cardiovascular diseases, and neurological disorders. For instance, overexpression of miR-155 is linked to various cancers, making it a potential diagnostic marker and therapeutic target. Similarly, lncRNAs like MALAT1 are associated with metastasis and poor prognosis in cancer patients.
