What Are the Challenges in Studying Non-Coding RNAs in Histology?
Studying non-coding RNAs in histology presents several challenges, including the complexity of ncRNA interactions, tissue-specific expression patterns, and the need for highly sensitive and specific detection methods. Additionally, the functional validation of ncRNAs requires sophisticated experimental approaches to elucidate their mechanisms of action and biological relevance. Advances in single-cell RNA sequencing and spatial transcriptomics are helping to overcome some of these challenges by providing high-resolution insights into ncRNA expression and function within tissues.
