What are the main components of the hippocampal circuitry?
The hippocampal circuitry is primarily composed of the following elements:
1. Dentate Gyrus: This region receives input from the entorhinal cortex via the perforant path. It consists of granule cells, which project to the CA3 region. 2. CA3 Region: Characterized by pyramidal neurons, the CA3 region receives input from the dentate gyrus and sends projections to the CA1 region through the Schaffer collateral pathway. 3. CA1 Region: Another region with pyramidal neurons, the CA1 receives input from CA3 and projects to the subiculum and entorhinal cortex. 4. Subiculum: Acts as the main output region of the hippocampus, sending information back to the entorhinal cortex and other brain regions.