Antioxidants play a vital role in maintaining tissue health by neutralizing free radicals and preventing oxidative damage. They can be enzymatic, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase, or non-enzymatic, like vitamins C and E, carotenoids, and flavonoids. In histology, the presence and activity of these antioxidants are often measured to assess the oxidative status of tissues.