What Are the Clinical Implications of Decreased GFR?
Decreased GFR can lead to a range of clinical consequences, including: - Accumulation of waste products in the blood, leading to symptoms of uremia. - Fluid and electrolyte imbalances, which can affect various organ systems. - Increased risk of cardiovascular diseases due to hypertension and fluid overload. - Progression to end-stage renal disease (ESRD), requiring dialysis or kidney transplantation.