Histological examination of kidney biopsies is crucial for diagnosing conditions that lead to decreased GFR. Common techniques include: - Light microscopy to assess general structure and identify abnormalities such as sclerosis or fibrosis. - Immunofluorescence to detect immune complexes and other proteins that may indicate glomerulonephritis. - Electron microscopy to examine ultrastructural details, such as podocyte foot processes and GBM abnormalities.
