adaptive immune responses

How Do T Cells Recognize Antigens?

T cells recognize antigens through T cell receptors (TCRs) that bind to antigenic peptides presented by Major Histocompatibility Complex (MHC) molecules on the surface of antigen-presenting cells (APCs). There are two types of MHC molecules:
- MHC Class I: Present on all nucleated cells and present antigens to cytotoxic T cells.
- MHC Class II: Found on professional APCs like dendritic cells, macrophages, and B cells, and present antigens to helper T cells.

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