The primary advantages of the EVG stain include: - Specificity: It specifically stains elastic fibers, allowing for clear differentiation from other tissue components. - Clarity: The contrast provided by the combination of black (elastic fibers), red (collagen), and yellow (cytoplasm and muscle) enhances the visualization of tissue architecture. - Diagnostic Utility: Widely used in clinical pathology for diagnosing conditions involving elastic fibers, such as atherosclerosis, emphysema, and Marfan syndrome.