Are there any potential histological markers for monitoring ADT effectiveness?
Yes, certain histological markers can be monitored to assess the effectiveness of ADT. These include:
Prostate-Specific Antigen (PSA): Although primarily a serum marker, PSA levels can correlate with histological changes in the prostate. Cell proliferation markers: A decrease in markers like Ki-67 indicates reduced cellular proliferation. Apoptotic markers: An increase in markers such as caspase-3 can indicate heightened apoptosis in response to ADT.