Tissue Validation: Before sequencing, histological examination confirms the presence of tumor cells and assesses the percentage of cancerous vs. normal cells. Subtype Classification: Histological analysis helps in classifying cancers into subtypes, which can be correlated with genomic data to identify unique molecular signatures. Prognostic and Diagnostic Biomarkers: Histological features can be correlated with genomic alterations to identify biomarkers that predict disease outcome or response to therapy.
