Why is Antigen Heterogeneity Important in Histology?
In histology, precise identification and classification of tissues and cells are essential. Antigen heterogeneity can complicate this process by causing variations in staining patterns during immunohistochemistry (IHC) or immunofluorescence techniques. Recognizing and understanding this heterogeneity can improve the accuracy of diagnoses, particularly in complex cases such as cancers where different regions of a tumor might express different antigens.
