What is the Role of TGF-β in the Extracellular Matrix (ECM)?
TGF-β is a major regulator of the extracellular matrix (ECM), which provides structural support to tissues. It stimulates the production of ECM components such as collagen and fibronectin while inhibiting the degradation of these components. This regulatory function is critical during wound healing and fibrosis, where TGF-β promotes tissue repair and scar formation.