What is the Role of Hedgehog Ligands in Embryonic Development?
During embryonic development, Hedgehog ligands are vital for the patterning and growth of various tissues and organs. For example, Sonic hedgehog (Shh) regulates the development of the neural tube, limbs, and somites. Indian hedgehog (Ihh) is important for endochondral ossification and the development of bones, while Desert hedgehog (Dhh) is involved in the development of the gonads.