Cripto, also known as Cripto-1 or TDGF-1, is a member of the epidermal growth factor-Cripto/FRL-1/Cryptic (EGF-CFC) family of signaling molecules. It is a glycosylphosphatidylinositol (GPI)-anchored protein that plays a critical role in various developmental processes, including embryogenesis, organ development, and tissue homeostasis.