What are the Clinical Implications of CYP2C9 Activity?
The activity of CYP2C9 has significant clinical implications, particularly in the context of pharmacogenomics. Variations in the CYP2C9 gene can lead to differences in drug metabolism rates, affecting drug efficacy and toxicity. For instance, individuals with certain CYP2C9 polymorphisms may require adjusted dosing of medications such as warfarin to avoid adverse effects.
