What histological changes are seen in neurodegenerative diseases?
Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease show distinct histological features. In Alzheimer's disease, there is the presence of amyloid plaques and neurofibrillary tangles. In Parkinson's disease, there is a loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies. These histological markers are crucial for diagnosis and understanding the progression of these diseases.
