How are Interstitial Cells Identified Histologically?
Histologically, interstitial cells can be identified based on their location and morphology. In the testes, Leydig cells are large, polygonal cells with a central round nucleus and eosinophilic cytoplasm. They often contain lipid droplets and Reinke crystals. Special stains and immunohistochemistry techniques can also be used to identify specific markers like LH receptors and enzymes involved in steroidogenesis.