How does aging impact the musculoskeletal system histologically?
The musculoskeletal system experiences several histological changes with aging. There is a reduction in the number and size of muscle fibers, leading to sarcopenia. Bone tissue shows a decrease in osteoblast activity and an increase in osteoclast activity, contributing to conditions like osteoporosis. Cartilage becomes thinner and less resilient due to a decrease in proteoglycans and collagen.
