What are the histological changes associated with aging?
Aging leads to a variety of histological changes in tissues and organs. Common alterations include a decrease in cell proliferation, increased cellular senescence, and the accumulation of cellular debris. There is often a reduction in the elasticity of tissues due to a decrease in collagen and elastin fibers. Additionally, there is an increase in the deposition of extracellular matrix components, which can lead to fibrosis.
