Several techniques are employed for scaffold fabrication, each with its advantages and limitations. Some of the common techniques include:
Electrospinning: This technique creates fibrous scaffolds that closely resemble the ECM. It is widely used for its simplicity and ability to produce nanofibers. 3D Printing: Also known as additive manufacturing, this technique allows for precise control over scaffold architecture and porosity. It is highly versatile and can fabricate complex structures. Solvent Casting: This involves dissolving the polymer in a solvent, casting it into a mold, and then removing the solvent to form a scaffold. It is suitable for creating thin films and membranes. Freeze-Drying: This technique involves freezing a polymer solution and then sublimating the solvent to create a porous scaffold. It is useful for creating highly porous structures.