What is the Biological Significance of KMTs in Tissue Differentiation?
During tissue differentiation, KMTs play a pivotal role by establishing and maintaining lineage-specific gene expression patterns. For instance, the differentiation of stem cells into specialized cell types involves extensive chromatin remodeling driven by KMT-mediated methylation. Aberrations in KMT function can lead to improper cell differentiation and are often implicated in various diseases, including cancer.
