What are the Key Components of the Neural Stem Cell Niche?
The neural stem cell niche is composed of various cellular and extracellular components:
Neural stem cells themselves, which are the primary residents. Ependymal cells that line the ventricles and provide structural support. Astrocytes that secrete growth factors and cytokines. Endothelial cells that form blood vessels and contribute to the blood-brain barrier. The extracellular matrix (ECM) which provides a scaffold and biochemical cues.