In histological sections, synapses can be identified by the presence of presynaptic and postsynaptic densities, synaptic vesicles, and the synaptic cleft. The presynaptic terminal contains synaptic vesicles filled with neurotransmitters, while the postsynaptic density contains receptors and associated proteins. The synaptic cleft is the space between the presynaptic and postsynaptic membranes where neurotransmitter release and binding occur.
