What are the Clinical Implications of Hemoglobin Variants?
The clinical implications of hemoglobin variants can vary widely:
Sickle Cell Disease: Chronic pain, anemia, and increased risk of infections and organ damage. Hemoglobin C Disease: Mild to moderate hemolytic anemia and splenomegaly. Hemoglobin E Disease: Generally mild symptoms, but can complicate other hemoglobinopathies.