What are the Common Causes of Synaptic Alterations?
Synaptic alterations can be caused by various factors, including aging, trauma, and diseases. Neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are characterized by significant synaptic loss and dysfunction. Moreover, traumatic brain injury (TBI) can lead to acute and chronic synaptic changes. Aging is also associated with a natural decline in synaptic density and plasticity.
