What are the Molecular Mechanisms Involved in Synaptic Alterations?
The molecular mechanisms underlying synaptic alterations involve a complex interplay of signaling pathways, cytoskeletal dynamics, and protein synthesis. Calcium signaling plays a critical role in synaptic plasticity by regulating neurotransmitter release and receptor trafficking. Additionally, the actin cytoskeleton is essential for the structural remodeling of synapses. Protein synthesis, particularly local synthesis at the synapse, is crucial for maintaining synaptic function and plasticity.