What are the Clinical Implications of Initiator Caspases?
The clinical implications of initiator caspases are profound. For instance, therapeutic strategies that target caspase-8 have been explored in the treatment of cancers that evade apoptosis. Similarly, inhibitors of caspase-9 are being investigated for their potential to protect neurons from apoptosis in diseases like Alzheimer's Disease and Parkinson's Disease. Understanding the regulation of these caspases can also provide insights into autoimmune diseases and chronic inflammatory conditions.
