Why are Initiator Caspases Important in Histology?
In the context of histology, understanding initiator caspases is crucial for studying tissue homeostasis and the pathological changes associated with various diseases. For instance, the deregulation of apoptosis is a hallmark of cancer, where caspases may be either overly active or inhibited, leading to uncontrolled cell proliferation. Similarly, in neurodegenerative diseases, excessive activation of initiator caspases can result in the loss of neurons.
