What are the Challenges in Targeting Cellular Pathways?
One of the main challenges in targeting cellular pathways is the complexity and redundancy of these networks. Multiple pathways can compensate for the inhibition of a single target, leading to drug resistance. Additionally, therapeutic targets may be differentially expressed in various tissues, complicating the development of specific and effective treatments. Histological studies are essential for understanding these complexities and developing strategies to overcome these challenges.
