What are Some Examples of Therapeutic Targets in Cancer?
In cancer, therapeutic targets often include oncogenes, tumor suppressor genes, and growth factor receptors. For example, the HER2/neu receptor is overexpressed in certain types of breast cancer and can be targeted by specific drugs like trastuzumab. Similarly, EGFR mutations in non-small cell lung cancer can be targeted by tyrosine kinase inhibitors. Histological analysis of tumor tissues helps in identifying these and other relevant targets.