In histology, the extracellular matrix (ECM) plays a crucial role in maintaining the structural integrity and function of tissues. Fibrillin-1, produced by the fbn1 gene, is an essential component of the ECM, particularly in connective tissues such as the skin, blood vessels, and ligaments. It interacts with other ECM proteins like elastin to form elastic fibers, which are vital for tissue elasticity and resilience.
