In the realm of histology, Dutcher bodies are intranuclear inclusions often found in plasma cells. They are composed of immunoglobulin and are considered a hallmark of certain hematologic malignancies, such as multiple myeloma and Waldenström's macroglobulinemia. These inclusions are visualized as clear, rounded, or oval structures within the nucleus of the cell, sometimes giving the appearance of a pseudo-inclusion due to their location.
