Dutcher bodies are typically identified using various staining techniques in histological examinations. Hematoxylin and eosin (H&E) staining is commonly employed, which highlights these bodies as eosinophilic (pink) structures within the nucleus. Additionally, special stains such as periodic acid-Schiff (PAS) can further confirm the presence of immunoglobulin. Immunohistochemistry can also be utilized to identify the specific types of immunoglobulins present.
