What are the Challenges in Identifying Dutcher Bodies?
One of the challenges in identifying Dutcher bodies is differentiating them from other types of intranuclear inclusions or artifacts. Proper staining techniques and the use of immunohistochemistry are essential for accurate identification. Additionally, the expertise of a pathologist is crucial in distinguishing these bodies from other similar-appearing structures. False positives can occur if the staining is not performed correctly or if the tissue sample is not adequately preserved.
