Aging is associated with various histological changes across different tissues. In the skin, aging leads to reduced collagen and elastin fibers, resulting in decreased elasticity and increased wrinkling. In the musculoskeletal system, there is a reduction in muscle mass and an increase in connective tissue, contributing to decreased strength and mobility. Additionally, aging neurons exhibit accumulation of intracellular inclusions like lipofuscin, and there is a loss of synaptic connections, affecting cognitive function.
