Therapeutic strategies to address hypoxia include the use of oxygen carriers, like hemoglobin-based oxygen carriers or perfluorocarbons, to improve oxygen delivery to tissues. Additionally, drugs that inhibit HIF activity are being explored to counteract the adverse effects of hypoxia in diseases such as cancer. Histological analysis plays a pivotal role in evaluating the efficacy of these treatments by assessing changes in tissue oxygenation and cellular morphology.
