How do NSAIDs influence cartilage and bone tissues?
In joint tissues, NSAIDs can impact cartilage and bone cells. Prostaglandins are involved in the regulation of bone turnover and cartilage homeostasis. Chronic use of NSAIDs may alter these processes, potentially leading to histological changes such as decreased cartilage synthesis and increased bone resorption. These changes might contribute to conditions like osteoarthritis.
